Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 13/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | NCF1 | P14598 | 1/20 | 0.60 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12660101 | 0.94 | LMNA (0.56) | CHKACA2NCF1PRMT6KDM4E | |
| SCHEMBL12853768 | 0.90 | HRH3 (0.55) | CHKACA2NCF1PRMT6KDM4E | |
| SCHEMBL15127542 | 0.84 | CHKA (0.51) | CHKACA2NCF1PRMT6KDM4E | |
| SCHEMBL19997251 | 0.83 | HSP90AA1 (0.54) | CHKACA2NCF1PRMT6KDM4E | |
| SCHEMBL19675099 | 0.83 | LMNA (0.56) | CHKACA2NCF1PRMT6LMNA | |
| SCHEMBL12853700 | 0.81 | SMN1; SMN2 (0.57) | NCF1KDM4EHSP90AA1HSP90AB1 | |
| SCHEMBL14615038 | 0.80 | CHKA (0.57) | CHKACA2NCF1PRMT6KDM4E | |
| SCHEMBL15893964 | 0.80 | HSP90AA1 (0.53) | CHKACA2NCF1PRMT6KDM4E | |
| SCHEMBL15127555 | 0.80 | HRH3 (0.50) | CHKACA2NCF1PRMT6KDM4E | |
| SCHEMBL25251135 | 0.79 | HSP90AA1 (0.51) | CHKACA2NCF1PRMT6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2073804-B1 | HYDROXY-SUBSTITUTED BENZOIC ACID AMIDE COMPOUNDS FOR USE IN THE TREATMENT OF PAIN | ASTEX THERAPEUTICS LTD (GB) | 2017-09-13 | — | — | EP | disclosed |