Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2706309 | 0.90 | ALDH1A1 (0.35) | TP53ALDH1A1LMNAGLAMEN1 | |
| SCHEMBL9977257 | 0.87 | ALDH1A1 (0.33) | TP53ALDH1A1LMNAGLAMEN1 | |
| SCHEMBL13070715 | 0.84 | HDAC8 (0.32) | ALDH1A1LMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL9281762 | 0.82 | ALDH1A1 (0.41) | TP53ALDH1A1LMNAGLAMEN1 | |
| SCHEMBL9213899 | 0.79 | KMT2A (0.43) | TP53ALDH1A1LMNAGLAMEN1 | |
| SCHEMBL2708771 | 0.79 | KMT2A (0.43) | TP53ALDH1A1LMNAGLAMEN1 | |
| SCHEMBL690316 | 0.77 | ALDH1A1 (0.39) | TP53ALDH1A1LMNAGLAMEN1 | |
| SCHEMBL15746346 | 0.76 | ALDH1A1 (0.35) | TP53ALDH1A1LMNAGLAMEN1 | |
| SCHEMBL690647 | 0.76 | ALDH1A1 (0.38) | TP53ALDH1A1LMNAGLAMEN1 | |
| SCHEMBL690646 | 0.76 | ALDH1A1 (0.38) | TP53ALDH1A1LMNAGLAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3002281-B1 | ANTIVIRAL COMPOUNDS | GILEAD PHARMASSET LLC (US) | 2017-09-13 | — | — | EP | disclosed |