SCHEMBL19340002

SCHEMBL19340002

C=C(c1cccc(C(=C)C(C)(C)C)c1)C(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
ATM Q13315 1/20 0.36
FURIN P09958 1/20 0.34
ACHE P22303 3/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
TSHR P16473 1/20 0.33
HTT P42858 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19340042 0.89 FURIN (0.33) NPSR1L3MBTL1TDP1ATMFURIN
SCHEMBL19340037 0.89 NPSR1 (0.33) NPSR1L3MBTL1TDP1ATMACHE
SCHEMBL16230721 0.85 CES2 (0.50) ACHEHTTHDAC6
SCHEMBL965081 0.82 ATM (0.40) NPSR1TDP1ATMTSHRLMNA
SCHEMBL167439 0.76 FURIN (0.43) L3MBTL1TDP1ATMFURINTSHR
SCHEMBL15780745 0.75 CA1 (0.46)
SCHEMBL28013821 0.75 CES1 (0.39) L3MBTL1TDP1ATMACHEHDAC6
SCHEMBL6252421 0.74 FURIN (0.41) L3MBTL1TDP1ATMFURINTSHR
SCHEMBL17421702 0.74 FURIN (0.41) L3MBTL1TDP1ATMFURINTSHR
SCHEMBL30834584 0.74 FURIN (0.41) L3MBTL1TDP1ATMFURINTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9976063-B2 Polyarylether ketone imide sulfone adhesives THE BOEING COMPANY (US) 2018-05-22 US disclosed
US-20170260332-A1 POLYARYLETHER KETONE IMIDE ADHESIVES THE BOEING COMPANY 2017-09-14 US disclosed
US-20170260432-A1 POLYARYLETHER KETONE IMIDE SULFONE ADHESIVES THE BOEING COMPANY 2017-09-14 US disclosed