Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24186598 | 0.77 | GSK3A (0.34) | GSK3AGSK3BALDH1A1 | |
| SCHEMBL22728277 | 0.71 | SMN1; SMN2 (0.40) | ALDH1A1 | |
| SCHEMBL20668468 | 0.71 | MEN1 (0.37) | — | |
| SCHEMBL6895559 | 0.69 | — | — | |
| SCHEMBL20734016 | 0.67 | — | — | |
| SCHEMBL13342621 | 0.67 | — | — | |
| SCHEMBL7945735 | 0.67 | — | — | |
| SCHEMBL23894741 | 0.67 | GSK3A (0.38) | GSK3AGSK3B | |
| SCHEMBL11205274 | 0.66 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL14872073 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021143677-A1 | FUSED RING SUBSTITUTED AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION, AND USE THEREOF | 青岛清原化合物有限公司 | 2021-07-22 | — | — | WO | disclosed |
| WO-2020190760-A1 | IMMUNOCONJUGATES TARGETING CEA | BOLT BIOTHERAPEUTICS, INC. (US) | 2020-09-24 | — | — | WO | disclosed |
| US-10780096-B2 | Pyrrolobenzodiazepine-antibody conjugates | ADC THERAPEUTICS SA (CH) | 2020-09-22 | — | — | US | disclosed |
| US-20170258934-A1 | PYRROLOBENZODIAZEPINE-ANTIBODY CONJUGATES | OWL ROCK OPPORTUNISTIC MASTER FUND I, L.P. | 2017-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170258934-A1 | PYRROLOBENZODIAZEPINE-ANTIBODY CONJUGATES | IL2RA, CD2, CD4 | GSK3A 3987/4885GSK3B 3561/4885ALDH1A1 375/4885 |
| US-10780096-B2 | Pyrrolobenzodiazepine-antibody conjugates | IL2RA, CD2, CD4 | GSK3A 3987/4885GSK3B 3561/4885ALDH1A1 375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.