SCHEMBL19340280

SCHEMBL19340280

CC1(C)c2ccccc2N(c2cc(C#N)c(-c3c(C#N)cc(N4c5ccccc5C(C)(C)c5ccccc54)cc3C#N)c(C#N)c2)c2ccccc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 5/20 0.39
ITGB2 P05107 1/20 0.37
ICAM1 P05362 1/20 0.37
ITGAL P20701 1/20 0.37
KMT2A Q03164 6/20 0.37
MEN1 O00255 5/20 0.37
HTT P42858 2/20 0.37
MAPT P10636 2/20 0.37
CRHBP P24387 1/20 0.37
CRHR2 Q13324 1/20 0.37
KEAP1 Q14145 1/20 0.37
NFE2L2 Q16236 1/20 0.37
CYP1A2 P05177 2/20 0.35
KDM4E B2RXH2 1/20 0.35
CYP2D6 P10635 1/20 0.35
LMNA P02545 2/20 0.33
AR P10275 1/20 0.33
NPSR1 Q6W5P4 2/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20437400 0.93 PGR (0.36) PGRITGB2ICAM1ITGALKMT2A
SCHEMBL20437402 0.85 PGR (0.39) PGRITGB2ICAM1ITGALKMT2A
SCHEMBL19345274 0.85 PGR (0.43) PGRKMT2AMEN1HTTMAPT
SCHEMBL20437395 0.84 AR (0.32) PGRITGB2ICAM1ITGALKMT2A
SCHEMBL19344953 0.83 PGR (0.43) PGRITGB2ICAM1ITGALKMT2A
SCHEMBL13231494 0.83 PGR (0.43) PGRITGB2ICAM1ITGALKMT2A
SCHEMBL17955009 0.82 PGR (0.44) PGRKMT2AMEN1HTTMAPT
SCHEMBL19344994 0.82 PGR (0.43) PGRKMT2AMEN1HTTMAPT
SCHEMBL19340283 0.82 ITGB2 (0.33) ITGB2ICAM1ITGALKDM4ELMNA
SCHEMBL19340284 0.82 PDK2 (0.35) PGRITGB2ICAM1ITGALKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170263871-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC OPTOELECTRONIC DEVICE TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2017-09-14 US disclosed
US-20170263871-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC OPTOELECTRONIC DEVICE TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2017-09-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170263871-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC OPTOELECTRONIC DEVICE OR10J3, RPS10, OR51E2 PGR 1448/4885ITGB2 49/4885ICAM1 296/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.