Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25721528 | 1.00 | BRD4 (0.43) | BRD4MAPK1KMT2AMEN1ALDH1A1 | |
| SCHEMBL12432392 | 0.91 | BRD4 (0.44) | BRD4MAPK1KMT2AMEN1ALDH1A1 | |
| SCHEMBL17714976 | 0.90 | MAPK1 (0.48) | MAPK1KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL20286680 | 0.88 | MAPK1 (0.44) | MAPK1KMT2AMEN1ALDH1A1HSD17B10 | |
| SCHEMBL14310857 | 0.87 | BRD4 (0.44) | BRD4MAPK1KMT2AMEN1ALDH1A1 | |
| SCHEMBL25627495 | 0.85 | BRD4 (0.50) | BRD4MAPK1KMT2AMEN1ALDH1A1 | |
| SCHEMBL12574001 | 0.85 | BRD4 (0.59) | BRD4MAPK1KMT2AMEN1ALDH1A1 | |
| SCHEMBL16234042 | 0.84 | MEN1 (0.46) | BRD4KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL15744784 | 0.84 | BRD4 (0.48) | BRD4MAPK1KMT2AMEN1ALDH1A1 | |
| SCHEMBL14010049 | 0.83 | BRD4 (0.56) | BRD4MAPK1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180194898-A1 | HYGROMORPHIC POLYMERS AND COPOLYMERS HAVING HUMIDITY-DRIVEN MOTILITY | GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2018-07-12 | — | — | US | disclosed |
| US-9932445-B2 | Hygromorphic polymers and copolymers having humidity-driven motility | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2018-04-03 | — | — | US | disclosed |
| US-20170260334-A1 | HYGROMORPHIC POLYMERS AND COPOLYMERS HAVING HUMIDITY-DRIVEN MOTILITY | GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE | 2017-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180194898-A1 | HYGROMORPHIC POLYMERS AND COPOLYMERS HAVING HUMIDITY-DRIVEN MOTILITY | DNAH12, PARG, PARN | BRD4 2165/4885MAPK1 2432/4885KMT2A 1721/4885 |
| US-20170260334-A1 | HYGROMORPHIC POLYMERS AND COPOLYMERS HAVING HUMIDITY-DRIVEN MOTILITY | DNAH12, PARG, PARN | BRD4 2165/4885MAPK1 2432/4885KMT2A 1721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.