Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.39 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.39 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19331724 | 0.89 | HPGD (0.43) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL12493100 | 0.87 | HPGD (0.46) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL21748946 | 0.87 | HPGD (0.46) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL12492477 | 0.87 | HPGD (0.46) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL25568092 | 0.87 | HPGD (0.46) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL3084302 | 0.86 | HPGD (0.41) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL13709116 | 0.86 | EPHX1 (0.42) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| Acetic Acid SCHEMBL17687614 | 0.86 | HPGD (0.43) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL3744107 | 0.86 | NR1H2 (0.49) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL3744110 | 0.86 | NR1H2 (0.49) | HPGDMEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017156177-A1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | RAZE THERAPEUTICS, INC. (US) | 2017-09-14 | — | — | WO | disclosed |