Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17591626 | 0.93 | RAF1 (0.57) | RAF1BRAF | |
| SCHEMBL25984431 | 0.88 | RAF1 (0.63) | RAF1BRAF | |
| SCHEMBL17591614 | 0.87 | RAF1 (0.60) | RAF1BRAF | |
| SCHEMBL25702404 | 0.85 | RAF1 (0.64) | RAF1BRAF | |
| SCHEMBL22562092 | 0.85 | LMNA (0.54) | RAF1BRAF | |
| SCHEMBL25702125 | 0.85 | RAF1 (0.64) | RAF1BRAF | |
| SCHEMBL25984157 | 0.85 | RAF1 (0.69) | RAF1BRAF | |
| SCHEMBL25984306 | 0.84 | RAF1 (0.61) | RAF1BRAF | |
| SCHEMBL25984205 | 0.84 | RAF1 (0.63) | RAF1BRAF | |
| SCHEMBL21297361 | 0.84 | RAF1 (0.48) | RAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170260200-A1 | COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS | NOVARTIS VACCINES AND DIAGNOSTICS, INC. | 2017-09-14 | — | — | US | disclosed |
| US-20170260200-A1 | COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS | NOVARTIS VACCINES AND DIAGNOSTICS, INC. | 2017-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170260200-A1 | COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS | BRAF, RAF1, MAP3K20 | RAF1 2/4885BRAF 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.