Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19344351 | 0.90 | PIK3CD (0.47) | PIK3CDKDM4ENPC1FFAR1HTT | |
| SCHEMBL22476054 | 0.90 | PIK3CD (0.47) | PIK3CDKDM4ENPC1FFAR1HTT | |
| SCHEMBL22975128 | 0.80 | PIK3CD (0.45) | PIK3CDKDM4ENPC1FFAR1LMNA | |
| SCHEMBL19344365 | 0.80 | PIK3CD (0.45) | PIK3CDKDM4ENPC1FFAR1LMNA | |
| SCHEMBL19344366 | 0.78 | NPC1 (0.41) | PIK3CDKDM4ENPC1FFAR1HTT | |
| SCHEMBL22476057 | 0.76 | PIK3CD (0.81) | PIK3CD | |
| SCHEMBL22476055 | 0.76 | PIK3CD (0.81) | PIK3CD | |
| SCHEMBL19344379 | 0.76 | PIK3CD (0.59) | PIK3CDKDM4ENPC1HTTPIK3CA | |
| SCHEMBL19331508 | 0.75 | FFAR1 (0.40) | PIK3CDKDM4ENPC1FFAR1HTT | |
| SCHEMBL19331509 | 0.75 | NPC1 (0.40) | PIK3CDKDM4ENPC1FFAR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017155741-A1 | QUINOLINE ANALOGS AS PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | ZHEJIANG VIMGREEN PHARMA LTD. (CN) | 2017-09-14 | — | — | WO | disclosed |