Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 19/20 | 0.46 |
| ▸ | BACE2 | Q9Y5Z0 | 7/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3301389 | 0.85 | BACE1 (0.49) | BACE1BACE2 | |
| SCHEMBL3300948 | 0.85 | BACE1 (0.51) | BACE1BACE2 | |
| SCHEMBL1934929 | 0.84 | BACE1 (0.46) | BACE1BACE2 | |
| SCHEMBL7923822 | 0.84 | BACE1 (0.46) | BACE1BACE2 | |
| SCHEMBL1935330 | 0.83 | BACE1 (0.56) | BACE1BACE2 | |
| SCHEMBL12557814 | 0.83 | BACE1 (0.67) | BACE1BACE2 | |
| SCHEMBL1935328 | 0.83 | BACE1 (0.56) | BACE1BACE2 | |
| SCHEMBL1933963 | 0.83 | BACE1 (0.67) | BACE1BACE2 | |
| SCHEMBL7914943 | 0.82 | BACE1 (0.48) | BACE1BACE2 | |
| SCHEMBL1933735 | 0.82 | BACE1 (0.48) | BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2332943-A1 | NOVEL FUSED AMINODIHYDROTHIAZINE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2011-06-15 | — | — | EP | disclosed |