⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9749368 | 0.88 | MAPK1 (0.46) | — | |
| SCHEMBL1489583 | 0.84 | LMNA (0.37) | — | |
| SCHEMBL4726321 | 0.81 | — | — | |
| SCHEMBL13676319 | 0.75 | — | — | |
| SCHEMBL278331 | 0.75 | — | — | |
| SCHEMBL1922912 | 0.75 | — | — | |
| SCHEMBL3438658 | 0.69 | — | — | |
| SCHEMBL9145538 | 0.69 | — | — | |
| SCHEMBL44881 | 0.67 | — | — | |
| SCHEMBL22311884 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4395897-A1 | NOVEL RAS INHIBITORS | KHR Biotec GmbH (DE) | 2024-07-10 | — | — | EP | claimed |
| WO-2024056619-A1 | 1H-CYCLOPENTA[B]BENZOFURAN DERIVATIVES FOR THE PREVENTION AND TREATMENT OF VIRUS DISEASES | KHR Biotec GmbH (DE) | 2024-03-21 | — | — | WO | claimed |
| EP-4288429-A1 | LACTAMS AS CBL-B INHIBITORS | Genentech, Inc. (US) | 2023-12-13 | — | — | EP | claimed |
| US-20230079990-A1 | LACTAMS AS CBL-B INHIBITORS | GENENTECH, INC. (US) | 2023-03-16 | — | — | US | claimed |
| WO-2023030685-A1 | NOVEL RAS INHIBITORS | KHR Biotec GmbH (I. GR.) (DE) | 2023-03-09 | — | — | WO | claimed |
| US-20220143002-A1 | SULFUR-CONTAINING COMPOUND BASED ON GLUTARIMIDE SKELETON AND APPLICATION THEREOF | SHANGHAITECH UNIVERSITY (CN) | 2022-05-12 | — | — | US | claimed |
| EP-3932922-A1 | SULFUR-CONTAINING COMPOUND BASED ON GLUTARIMIDE SKELETON AND APPLICATION THEREOF | ShanghaiTech University (CN) | 2022-01-05 | — | — | EP | claimed |
| WO-2019063708-A1 | SUBSTITUTED 3-PHENYLQUINAZOLIN-4(3H)-ONES AND USES THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2019-04-04 | — | — | WO | claimed |
| WO-2019063704-A1 | SUBSTITUTED 3-PHENYLQUINAZOLIN-4(3H)-ONES AND USES THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2019-04-04 | — | — | WO | claimed |
| US-8362067-B2 | 3-aminoalkyl-1,3-dihydro-2H-indol-2-one derivatives, preparation thereof and therapeutic use thereof | SANOFI (FR) | 2013-01-29 | — | — | US | claimed |
| US-20050250808-A1 | Indoles, 1h-indazoles, 1,2-benzisoxazoles, 1,2-benzoisothiazoles, and preparation and uses thereof | MEMORY PHARMACEUTICAL CORPORATION | 2005-11-10 | — | — | US | claimed |
| US-20050159436-A1 | Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for the preparation thereof | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2005-07-21 | — | — | US | claimed |
| EP-1499619-A1 | BICYCLIC HETEROCYCLES, MEDICAMENTS CONTAINING THESE COMPOUNDS, THEIR USE, AND METHOD FOR THE PRODUCTION THEREOF | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2005-01-26 | — | — | EP | claimed |
| US-20040044014-A1 | Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for the preparation thereof | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-03-04 | — | — | US | claimed |
| WO-2003089439-A1 | BICYCLIC HETEROCYCLES, MEDICAMENTS CONTAINING THESE COMPOUNDS, THEIR USE, AND METHOD FOR THE PRODUCTION THEREOF | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2003-10-30 | — | — | WO | claimed |
| EP-0650488-A1 | QUINOLINE AND NAPHTHYRIDINE PRODRUGS | PFIZER INC. (US) | 1995-05-03 | — | — | EP | claimed |
| WO-1994002480-A1 | QUINOLINE AND NAPHTHYRIDINE PRODRUGS | PFIZER INC. (US) | 1994-02-03 | — | — | WO | claimed |
| EP-0215650-B1 | SUBSTITUTED BRIDGED-DIAZABICYCLOALKYL QUINOLONE CARBOXYLIC ACIDS | PFIZER INC. (US) | 1992-01-29 | — | — | EP | claimed |
| US-4861779-A | Anti-bacterial substituted bridged-diazabicycloalkyl quinolone carboxylic acids | PFIZER INC. (US) | 1989-08-29 | — | — | US | claimed |
| EP-0215650-A2 | Substituted bridged-diazabicycloalkyl quinolone carboxylic acids | PFIZER INC. (US) | 1987-03-25 | — | — | EP | claimed |