Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | LPL | P06858 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.33 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.33 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20768579 | 0.78 | KDM4E (0.42) | CYP1A2MAPTCA2 | |
| SCHEMBL20768578 | 0.78 | KDM4E (0.42) | CYP1A2MAPTCA2 | |
| SCHEMBL18844142 | 0.77 | SKP2 (0.43) | SKP2CNR1CNR2FFAR4LPL | |
| SCHEMBL18793781 | 0.77 | TDP1 (0.40) | CYP1A2 | |
| SCHEMBL30039662 | 0.76 | F2 (0.41) | CYP4Z1MAPT | |
| SCHEMBL20768626 | 0.76 | F2 (0.41) | CYP4Z1MAPT | |
| SCHEMBL20768627 | 0.76 | F2 (0.41) | CYP4Z1MAPT | |
| SCHEMBL7568519 | 0.75 | PDE10A (0.45) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| Hydrochloric Acid SCHEMBL5759186 | 0.72 | GRM1 (0.33) | CYP1A2MAPTCA2 | |
| SCHEMBL7929027 | 0.71 | NOS1 (0.42) | CNR1CNR2S1PR4S1PR1S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017156179-A1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | RAZE THERAPEUTICS, INC. (US) | 2017-09-14 | — | — | WO | disclosed |