SCHEMBL19349332

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19349269	0.93	BRAF (0.46)	NPC1LMNAPKMRETCDK8
	SCHEMBL19349446	0.91	RET (0.43)	NPC1LMNAPKMRETCDK8
	SCHEMBL19349306	0.91	BRAF (0.43)	NPC1LMNAPKMRETCDK8
	SCHEMBL19349542	0.90	RET (0.48)	NPC1LMNAPKMRETCDK8
	SCHEMBL19349513	0.89	BRAF (0.42)	RETCDK8BRAFKDRKIT
	SCHEMBL19349471	0.88	RET (0.40)	NPC1LMNAPKMRETCDK8
	SCHEMBL19349307	0.88	RET (0.39)	NPC1LMNAPKMRETCDK8
	SCHEMBL24081833	0.86	BRAF (0.39)	NPC1LMNAPKMRETCDK8
	SCHEMBL19349405	0.86	BRAF (0.45)	NPC1LMNAPKMCDK8BRAF
	SCHEMBL24081778	0.82	BRAF (0.43)	BRAF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.