Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | LAP3 | P28838 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19349696 | 0.95 | CYP3A4 (0.66) | CYP3A4L3MBTL1LAP3TDP1TSHR | |
| SCHEMBL31197927 | 0.86 | CYP3A4 (0.62) | CYP3A4L3MBTL1LAP3TDP1TSHR | |
| SCHEMBL20987291 | 0.80 | CYP3A4 (0.92) | CYP3A4L3MBTL1TDP1TSHRATM | |
| SCHEMBL31438893 | 0.80 | CYP3A4 (0.85) | CYP3A4L3MBTL1LAP3TDP1TSHR | |
| SCHEMBL8436558 | 0.80 | CYP3A4 (0.85) | CYP3A4L3MBTL1LAP3TDP1TSHR | |
| SCHEMBL4158111 | 0.80 | LAP3 (0.58) | LAP3S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL19955270 | 0.80 | LAP3 (0.58) | LAP3S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL10932158 | 0.80 | CYP3A4 (0.54) | CYP3A4L3MBTL1LAP3TDP1TSHR | |
| SCHEMBL10931757 | 0.80 | CYP3A4 (0.54) | CYP3A4L3MBTL1LAP3TDP1TSHR | |
| SCHEMBL28895751 | 0.78 | CYP3A4 (0.70) | CYP3A4L3MBTL1TDP1TSHRATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10081554-B2 | Use of amino-containing neutral phosphine extractant in extraction and separation of thorium and process of using same | CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2018-09-25 | — | — | US | claimed |
| US-20170267540-A1 | USE OF AMINO-CONTAINING NEUTRAL PHOSPHINE EXTRACTANT IN EXTRACTION AND SEPARATION OF THORIUM AND PROCESS OF USING SAME | CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2017-09-21 | — | — | US | claimed |
| US-10081554-B2 | Use of amino-containing neutral phosphine extractant in extraction and separation of thorium and process of using same | CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2018-09-25 | — | — | US | disclosed |
| US-20170267540-A1 | USE OF AMINO-CONTAINING NEUTRAL PHOSPHINE EXTRACTANT IN EXTRACTION AND SEPARATION OF THORIUM AND PROCESS OF USING SAME | CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2017-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10081554-B2 | Use of amino-containing neutral phosphine extractant in extraction and separation of thorium and process of using same | PHOSPHO1, PTMS, PRMT5 | CYP3A4 4355/4885L3MBTL1 1181/4885LAP3 161/4885 |
| US-20170267540-A1 | USE OF AMINO-CONTAINING NEUTRAL PHOSPHINE EXTRACTANT IN EXTRACTION AND SEPARATION OF THORIUM AND PROCESS OF USING SAME | PHOSPHO1, PTMS, PRMT5 | CYP3A4 4355/4885L3MBTL1 1181/4885LAP3 161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.