Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | SMARCA2 | P51531 | 5/20 | 0.51 |
| ▸ | SMARCA4 | P51532 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KCNQ3 | O43525 | 4/20 | 0.50 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.50 |
| ▸ | KCNE1 | P15382 | 4/20 | 0.50 |
| ▸ | KCNQ1 | P51787 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.46 |
| ▸ | TYK2 | P29597 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28577238 | 0.80 | SMARCA2 (0.56) | MEN1KMT2AHDAC4SMARCA2SMARCA4 | |
| SCHEMBL123501 | 0.78 | KCNQ3 (0.64) | MEN1KMT2AHDAC4SMARCA2SMARCA4 | |
| SCHEMBL28821933 | 0.78 | JAK2 (0.63) | MEN1KMT2AHDAC4SMARCA2SMARCA4 | |
| SCHEMBL16430855 | 0.77 | KCNQ3 (0.66) | MEN1KMT2ANPC1RAB9AKCNQ3 | |
| SCHEMBL4250912 | 0.76 | KCNQ3 (0.70) | HDAC4SMARCA2SMARCA4MAPTKCNQ3 | |
| SCHEMBL24771257 | 0.76 | NPC1 (0.65) | MEN1KMT2AMAPTKDM4ENPC1 | |
| SCHEMBL20774335 | 0.76 | NPC1 (0.57) | MEN1KMT2AMAPTKDM4ENPC1 | |
| SCHEMBL14051567 | 0.76 | NPC1 (0.60) | MEN1KMT2AHDAC4SMARCA2SMARCA4 | |
| SCHEMBL5897217 | 0.76 | LMNA (0.55) | MEN1KMT2AMAPTKDM4ENPC1 | |
| SCHEMBL5897079 | 0.75 | LMNA (0.54) | MEN1KMT2AMAPTKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017155844-A1 | HEPATITIS B ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2017-09-14 | — | — | WO | disclosed |