Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | GMNN | O75496 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL841233 | 0.89 | MCL1 (0.66) | MAOBMCL1LMNAGAAALDH1A1 | |
| SCHEMBL841232 | 0.89 | MCL1 (0.66) | MAOBMCL1LMNAGAAALDH1A1 | |
| SCHEMBL1934858 | 0.88 | MAOB (0.59) | MAOBMCL1LMNAGAAALDH1A1 | |
| SCHEMBL873592 | 0.80 | EGFR (0.59) | LMNAGAAALDH1A1KDM4EHPGD | |
| SCHEMBL841260 | 0.77 | KMT2A (0.60) | LMNAALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL1573453 | 0.77 | KMT2A (0.60) | LMNAALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL841259 | 0.77 | KMT2A (0.60) | LMNAALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL841782 | 0.77 | KMT2A (0.60) | LMNAALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL841781 | 0.77 | KMT2A (0.60) | LMNAALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL13678158 | 0.77 | MAOB (0.78) | MAOBMCL1LMNAGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2506852-A2 | INTERFERON THERAPIES IN COMBINATION WITH BLOCKADE OF STAT3 ACTIVATION | Board Of Regents, The University Of Texas System (US) | 2012-10-10 | — | — | EP | disclosed |
| WO-2011069141-A2 | INTERFERON THERAPIES IN COMBINATION WITH BLOCKADE OF STAT3 ACTIVATION | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2011-06-09 | — | — | WO | disclosed |