Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.59 |
| ▸ | USP9X | Q93008 | 2/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RGS12 | O14924 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL840572 | 0.89 | USP9X (0.66) | MAOBUSP9XMCL1LMNAGAA | |
| SCHEMBL840571 | 0.89 | USP9X (0.66) | MAOBUSP9XMCL1LMNAGAA | |
| SCHEMBL1935191 | 0.88 | MAOB (0.59) | MAOBMCL1LMNAGAAKDM4E | |
| SCHEMBL1934987 | 0.87 | USP9X (0.72) | MAOBUSP9XLMNAGAAKDM4E | |
| SCHEMBL1934787 | 0.80 | USP9X (0.68) | USP9XLMNAGAAKDM4EALDH1A1 | |
| Mol-4239 SCHEMBL1316581 | 0.77 | STAT3 (0.77) | USP9XLMNAKDM4EALDH1A1HPGD | |
| Mol-4239 SCHEMBL1318844 | 0.77 | STAT3 (0.77) | USP9XLMNAKDM4EALDH1A1HPGD | |
| Mol-4239 SCHEMBL29818004 | 0.77 | STAT3 (0.77) | USP9XLMNAKDM4EALDH1A1HPGD | |
| Mol-4239 SCHEMBL862248 | 0.77 | STAT3 (0.77) | USP9XLMNAKDM4EALDH1A1HPGD | |
| Mol-4239 SCHEMBL862020 | 0.77 | STAT3 (0.77) | USP9XLMNAKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2506852-A2 | INTERFERON THERAPIES IN COMBINATION WITH BLOCKADE OF STAT3 ACTIVATION | Board Of Regents, The University Of Texas System (US) | 2012-10-10 | — | — | EP | disclosed |
| WO-2011069141-A2 | INTERFERON THERAPIES IN COMBINATION WITH BLOCKADE OF STAT3 ACTIVATION | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2011-06-09 | — | — | WO | disclosed |