Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 5/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RARA | P10276 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.48 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5072219 | 0.92 | KDM4E (0.53) | PPARAPPARGMEN1ALDH1A1MAPT | |
| SCHEMBL7064779 | 0.92 | KDM4E (0.53) | PPARAPPARGMEN1ALDH1A1MAPT | |
| SCHEMBL1935282 | 0.92 | KDM4E (0.53) | PPARAPPARGMEN1ALDH1A1MAPT | |
| SCHEMBL3517818 | 0.92 | KDM4E (0.53) | PPARAPPARGMEN1ALDH1A1MAPT | |
| SCHEMBL28881046 | 0.88 | KDM4E (0.48) | PPARAPPARGTSHRALDH1A1MAPT | |
| SCHEMBL7262506 | 0.88 | PPARA (0.56) | PPARAPPARGTP53TSHRRARB | |
| SCHEMBL3459040 | 0.88 | PPARA (0.56) | PPARAPPARGTP53TSHRRARB | |
| SCHEMBL7271225 | 0.88 | PPARA (0.56) | PPARAPPARGTP53TSHRRARB | |
| SCHEMBL8516008 | 0.88 | PPARA (0.56) | PPARAPPARGTP53TSHRRARB | |
| SCHEMBL8515505 | 0.88 | PPARA (0.56) | PPARAPPARGTP53TSHRRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331665-B1 | GREASE COMPOSITION | SHELL INT RESEARCH (NL) | 2018-02-14 | — | — | EP | disclosed |
| US-9096813-B2 | Grease composition | SHELL OIL COMPANY (US) | 2015-08-04 | — | — | US | disclosed |
| US-20110195880-A1 | GREASE COMPOSITION | SHELL USA, INC. | 2011-08-11 | — | — | US | disclosed |
| EP-2331665-A1 | GREASE COMPOSITION | Shell Internationale Research Maatschappij B.V. (NL) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010037746-A1 | GREASE COMPOSITION | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2010-04-08 | — | — | WO | disclosed |