Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.44 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7064779 | 1.00 | KDM4E (0.53) | KDM4EALDH1A1HPGDL3MBTL1MAPT | |
| SCHEMBL3517818 | 1.00 | KDM4E (0.53) | KDM4EALDH1A1HPGDL3MBTL1MAPT | |
| SCHEMBL1935282 | 1.00 | KDM4E (0.53) | KDM4EALDH1A1HPGDL3MBTL1MAPT | |
| SCHEMBL1935283 | 0.92 | PPARA (0.49) | ALDH1A1MAPTKMT2APPARGPPARA | |
| SCHEMBL421539 | 0.90 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDL3MBTL1MAPT | |
| SCHEMBL26239641 | 0.88 | MGLL (0.50) | KDM4EALDH1A1HPGDL3MBTL1MAPT | |
| SCHEMBL35610 | 0.85 | MGLL (0.48) | KDM4EALDH1A1HPGDL3MBTL1MAPT | |
| SCHEMBL15173906 | 0.85 | MGLL (0.54) | KDM4EALDH1A1HPGDL3MBTL1MAPT | |
| SCHEMBL11419358 | 0.85 | CYP4A11 (0.59) | KDM4EALDH1A1HPGDL3MBTL1MAPT | |
| SCHEMBL8372362 | 0.84 | PRSS1 (0.42) | ALDH1A1MAPTKMT2APPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2131656-A2 | PHTHALAZINE DERIVATIVES | Forest Laboratories Holdings Limited (BM) | 2009-12-16 | — | — | EP | disclosed |
| WO-2008061108-A2 | PHTHALAZINE DERIVATIVES | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2008-05-22 | — | — | WO | disclosed |