Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 7/20 | 0.32 |
| ▸ | PYGL | P06737 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.30 |
| ▸ | GLB1 | P16278 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1934212 | 1.00 | SI (0.34) | SIFUCA1GBA1PYGLGAA | |
| SCHEMBL1934214 | 1.00 | SI (0.34) | SIFUCA1GBA1PYGLGAA | |
| SCHEMBL1934033 | 1.00 | SI (0.34) | SIFUCA1GBA1PYGLGAA | |
| SCHEMBL12237113 | 0.89 | MGAM (0.35) | SIGAA | |
| SCHEMBL11934324 | 0.86 | — | — | |
| SCHEMBL10104044 | 0.86 | — | — | |
| SCHEMBL14347141 | 0.86 | — | — | |
| SCHEMBL11946140 | 0.86 | — | — | |
| SCHEMBL3795114 | 0.86 | — | — | |
| SCHEMBL8592918 | 0.86 | SI (0.42) | SIGBA1PYGLGAAGBA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2506716-A1 | NOVEL TRICYCLIC COMPOUNDS | Abbott Laboratories (US) | 2012-10-10 | — | — | EP | disclosed |
| WO-2011068881-A1 | NOVEL TRICYCLIC COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-09 | — | — | WO | disclosed |