Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | STK17B | O94768 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18224247 | 0.86 | MAPT (0.59) | KMT2AMEN1KDM4EMAPTNPC1 | |
| SCHEMBL29880960 | 0.80 | GAA (0.50) | KMT2AMEN1KDM4EMAPTNPC1 | |
| SCHEMBL8100817 | 0.80 | GAA (0.50) | KMT2AMEN1KDM4EMAPTNPC1 | |
| SCHEMBL5649473 | 0.79 | KMT2A (1.00) | KMT2AMEN1KDM4EMAPTNPC1 | |
| SCHEMBL14701871 | 0.76 | ESR2 (0.46) | KMT2AMEN1KDM4EMAPTNPC1 | |
| SCHEMBL19387339 | 0.76 | ESR2 (0.46) | KMT2AMEN1KDM4EMAPTNPC1 | |
| SCHEMBL14671273 | 0.76 | MEN1 (0.48) | KMT2AMEN1KDM4EMAPTNPC1 | |
| SCHEMBL14671252 | 0.76 | ESR2 (0.46) | KMT2AMEN1KDM4EMAPTNPC1 | |
| SCHEMBL10800989 | 0.72 | APP (0.46) | KMT2AMEN1KDM4EMAPTCYP3A4 | |
| SCHEMBL8802445 | 0.70 | GAA (0.54) | KMT2AMEN1KDM4EMAPTESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2332527-A2 | Flavanoids and Isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2011-06-15 | — | — | EP | disclosed |