Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8100817 | 1.00 | GAA (0.50) | GAAMEN1KMT2AKDM4ECYP2C9 | |
| SCHEMBL501810 | 0.85 | GAA (0.65) | GAAMEN1KMT2ACYP2C9ATM | |
| Phosphine SCHEMBL23295992 | 0.84 | GAA (0.63) | GAAMEN1KMT2ACYP2C9ATM | |
| SCHEMBL8802445 | 0.83 | GAA (0.54) | GAAMEN1KMT2AKDM4EMAPT | |
| SCHEMBL20631015 | 0.83 | GAA (0.67) | GAAMEN1KMT2ACYP2C9ATM | |
| Phosphoric Acid SCHEMBL21596650 | 0.81 | GAA (0.56) | GAAMEN1KMT2ACYP2C9ATM | |
| SCHEMBL1935462 | 0.80 | KMT2A (0.64) | GAAMEN1KMT2AKDM4EMAPT | |
| Acetamide SCHEMBL10703945 | 0.80 | GAA (0.59) | GAAMEN1KMT2ACYP2C9ATM | |
| SCHEMBL571262 | 0.80 | GAA (0.68) | GAAMEN1KMT2AKDM4EMAPT | |
| SCHEMBL30595412 | 0.79 | GAA (0.54) | GAAMEN1KMT2ACYP2C9ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111670214-B | 3-phenyl-3H-1-benzofuran-2-one compounds and compositions comprising the same | 美利肯公司 | 2022-08-16 | — | — | CN | disclosed |