Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP7 | O15540 | 6/20 | 0.78 |
| ▸ | FABP5 | Q01469 | 5/20 | 0.78 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | P4HB | P07237 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19355091 | 0.88 | FABP7 (1.00) | FABP7FABP5GAAPOLBTSHR | |
| SCHEMBL18674131 | 0.83 | GAA (0.62) | FABP7FABP5GAAPOLBTSHR | |
| SCHEMBL26795351 | 0.82 | FABP7 (0.60) | FABP7FABP5GAAPOLBTSHR | |
| SCHEMBL26796098 | 0.82 | FABP7 (0.60) | FABP7FABP5GAAPOLBTSHR | |
| SCHEMBL26036695 | 0.82 | FABP7 (0.81) | FABP7FABP5GAAPOLBTSHR | |
| SCHEMBL31145528 | 0.81 | FABP7 (0.61) | FABP7FABP5TSHRALDH1A1MAPK1 | |
| SCHEMBL19201560 | 0.80 | POLB (0.78) | FABP7FABP5GAAPOLBTSHR | |
| SCHEMBL13432587 | 0.80 | FABP7 (0.73) | FABP7FABP5GAAPOLBTSHR | |
| SCHEMBL7757018 | 0.80 | FABP7 (0.73) | FABP7FABP5GAAPOLBTSHR | |
| SCHEMBL12114007 | 0.80 | FABP7 (0.73) | FABP7FABP5GAAPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10968163-B2 | Alpha-truxillic acid derivatives and pharmaceutical compositions thereof | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2021-04-06 | — | — | US | disclosed |
| WO-2017156354-A1 | α-TRUXILLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2017-09-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10968163-B2 | Alpha-truxillic acid derivatives and pharmaceutical compositions thereof | FABP1, FABP2, FABP4 | FABP7 4/4885FABP5 6/4885GAA 2726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.