SCHEMBL19356

SCHEMBL19356

C=C(C)/C=C\C(=C)N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL852140 0.82
SCHEMBL852141 0.82
SCHEMBL19661047 0.82
SCHEMBL852156 0.82
SCHEMBL16615842 0.75
SCHEMBL17029292 0.75
SCHEMBL18600034 0.75
SCHEMBL10504642 0.75
SCHEMBL12330201 0.75 ALDH1A1 (0.35)
SCHEMBL19221189 0.75 TDP1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12030081-B2 Large lateral scale two-dimensional materials and other thin films, and associated systems and methods THE UNIVERSITY OF CHICAGO (US) 2024-07-09 US disclosed
US-20220388026-A1 LARGE LATERAL SCALE TWO-DIMENSIONAL MATERIALS AND OTHER THIN FILMS, AND ASSOCIATED SYSTEMS AND METHODS THE UNIVERSITY OF CHICAGO (US) 2022-12-08 US disclosed
US-9233057-B2 Particular quinone direct dyes, dye composition comprising at least one such dye, implementation process therefor and use thereof L'OREAL (FR) 2016-01-12 US disclosed
US-20140360523-A1 PARTICULAR QUINONE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, IMPLEMENTATION PROCESS THEREFOR AND USE THEREOF L'OREAL (FR) 2014-12-11 US disclosed
WO-2012027261-A1 SULFONYLPIPERAZINE DERIVATIVES THAT INTERACT WITH GLUCOKINASE REGULATORY PROTEIN FOR THE TREATMENT OF DIABETES AMGEN INC. (US) 2012-03-01 WO disclosed
US-20100048561-A1 QUINAZOLINES FOR PDK1 INHIBITION NOVARTIS VACCINES & DIAGNOSTICS, INC. (US) 2010-02-25 US disclosed