Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16411271 | 0.78 | TSHR (0.33) | TSHRTHRBGAA | |
| SCHEMBL22995432 | 0.76 | TSHR (0.32) | TSHRTHRBGAA | |
| SCHEMBL3009868 | 0.74 | TSHR (0.36) | TSHRTHRBGAA | |
| SCHEMBL8626986 | 0.65 | GRIN2D (0.48) | TSHRTHRB | |
| SCHEMBL15059086 | 0.64 | TSHR (0.39) | TSHRTHRB | |
| SCHEMBL16411503 | 0.64 | — | — | |
| Ammonia Solution, Strong SCHEMBL20492546 | 0.62 | TSHR (0.37) | TSHRTHRB | |
| SCHEMBL2807710 | 0.60 | TSHR (0.41) | TSHRTHRBGAA | |
| SCHEMBL25338622 | 0.60 | TSHR (0.41) | TSHRTHRB | |
| Hexane SCHEMBL3968207 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170260565-A1 | PROPEPTIDE-LUCIFERASE FUSION PROTEINS AND METHODS OF USE THEREOF | The Broad Institute Inc. | 2017-09-14 | — | — | US | disclosed |