Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.33 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28008290 | 0.97 | TSHR (0.47) | TSHRTHRBLMNADNM1SLC22A1 | |
| Ammonia Solution, Strong SCHEMBL27517072 | 0.97 | TSHR (0.39) | TSHRTHRBLMNADNM1SLC22A1 | |
| SCHEMBL8791134 | 0.88 | TSHR (0.37) | TSHRTHRBLMNADNM1SIRT2 | |
| SCHEMBL11786898 | 0.88 | TSHR (0.37) | TSHRTHRBLMNADNM1SLC22A1 | |
| SCHEMBL28346839 | 0.88 | TSHR (0.37) | TSHRTHRBLMNADNM1SLC22A1 | |
| SCHEMBL25392376 | 0.86 | TSHR (0.35) | TSHRTHRBSIRT2 | |
| SCHEMBL25390367 | 0.86 | TSHR (0.35) | TSHRTHRBSIRT2 | |
| SCHEMBL5712582 | 0.86 | TSHR (0.35) | TSHRTHRBSIRT2 | |
| SCHEMBL25392277 | 0.86 | TSHR (0.35) | TSHRTHRBSIRT2 | |
| SCHEMBL21805758 | 0.86 | TSHR (0.42) | TSHRTHRBLMNADNM1SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115896821-A | Electrically promoting CO 2 Method for synthesizing diacid compound by participating in ring-opening double-carboxylation reaction of small ring compound | 四川大学 | 2023-04-04 | — | — | CN | disclosed |
| EP-1988587-B1 | Oxocarbon, pseudo oxocarbon and radialene compounds and their use | NOVALED GMBH (DE) | 2016-12-07 | — | — | EP | disclosed |
| CN-101828552-B | Methods of blocking ethylene response in plants using cyclopropene derivatives | UNIV NORTH CAROLINA STATE | 2014-09-24 | — | — | CN | disclosed |
| CN-1450859-B | Method for blocking ethylene response in plants using cyclopropene derivatives | UNIV NORTH CAROLINA STATE | 2011-08-03 | — | — | CN | disclosed |
| CN-101828552-A | Method with the cyclopropene derivatives blocking ethylene response in plants | UNIV NORTH CAROLINA STATE | 2010-09-15 | — | — | CN | disclosed |
| US-7660677-B2 | Method of designing physiologically active peptide and use thereof | Tanuma, Sei-ichi (JP) | 2010-02-09 | — | — | US | disclosed |
| US-7141674-B2 | Anti-inflammatory compounds | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2006-11-28 | — | — | US | disclosed |
| US-20060217891-A1 | Method of designing physiologically active peptide and use thereof | SEI-ICHI TANUMA (JP) | 2006-09-28 | — | — | US | disclosed |
| US-20040082601-A1 | Anti-inflammatory compounds | SCOTT MALCOLM K (US) | 2004-04-29 | — | — | US | disclosed |
| EP-1233669-B1 | BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES | UNIV NORTH CAROLINA STATE (US) | 2004-02-25 | — | — | EP | disclosed |
| EP-0966430-A1 | ANTI-INFLAMMATORY COMPOUNDS | Ortho-Mcneil Pharmaceutical Corp. (US) | 1999-12-29 | — | — | EP | disclosed |
| WO-1999033786-A1 | ANTI-INFLAMMATORY COMPOUNDS | ORTHO-MCNEIL PHARMACEUTICAL CORPORATION (US) | 1999-07-08 | — | — | WO | disclosed |
| US-5663207-A | ADMINISTERING TO INHIBIT DEVELOPMENT OF BREAST TUMOR | RESEARCH CORPORATION TECHNOLOGIES (US) | 1997-09-02 | — | — | US | disclosed |
| US-5397802-A | Gem-dichlorocyclopropanes as antitumor agents | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-03-14 | — | — | US | disclosed |
| US-5158597-A | Herbicidal 12-substituted 12H-dibenzo[d,g]dioxocin-6-carboxylic acids | THE DOW CHEMICAL COMPANY (US) | 1992-10-27 | — | — | US | disclosed |
| US-5071465-A | Preemergence; postemergence | THE DOW CHEMICAL COMPANY (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0403026-A1 | 12-Substituted-12H-dibenzo(D,G)(1,3)dioxocin-6-carboxylic acids, herbicidal compositions, and a method of controlling undesirable vegetation | DowElanco (US) | 1990-12-19 | — | — | EP | disclosed |
| US-4938790-A | Herbicidal 12-substituted 12H-dibenzo(D,G)(1,3)dioxocin-6-carboxylic acids | THE DOW CHEMICAL COMPANY (US) | 1990-07-03 | — | — | US | disclosed |
| US-4133821-A | Alkylidenediquinocyclopropanes and Diarylcyclopropenes and method for preparation | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1979-01-09 | — | — | US | disclosed |
| US-3941833-A | CARDIOVASCULAR DISORDERS | SOCIETE ANONYME DITE: HEXACHIMIE (FR) | 1976-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082601-A1 | Anti-inflammatory compounds | TNF, PTGES, PTGES2 | TSHR 4802/4885THRB 4495/4885LMNA 1869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.