⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1935702 | 1.00 | — | — | |
| SCHEMBL3301335 | 0.74 | — | — | |
| SCHEMBL3301324 | 0.74 | — | — | |
| SCHEMBL18087827 | 0.73 | — | — | |
| SCHEMBL2265079 | 0.73 | — | — | |
| SCHEMBL18085184 | 0.73 | FFAR1 (0.33) | — | |
| SCHEMBL1935251 | 0.73 | — | — | |
| SCHEMBL16940581 | 0.73 | FFAR1 (0.33) | — | |
| SCHEMBL15516988 | 0.70 | TSHR (0.44) | — | |
| SCHEMBL18085576 | 0.70 | TSHR (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110207723-A1 | NOVEL FUSED AMINODIHYDROTHIAZINE DERIVATIVE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-08-25 | — | — | US | disclosed |
| EP-2332943-A1 | NOVEL FUSED AMINODIHYDROTHIAZINE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2011-06-15 | — | — | EP | disclosed |