⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3301324 | 1.00 | — | — | |
| SCHEMBL7922351 | 0.81 | TDP1 (0.37) | — | |
| SCHEMBL9913122 | 0.81 | TDP1 (0.37) | — | |
| SCHEMBL16940581 | 0.79 | FFAR1 (0.33) | — | |
| SCHEMBL18085184 | 0.79 | FFAR1 (0.33) | — | |
| SCHEMBL2334401 | 0.76 | ALDH1A1 (0.31) | — | |
| SCHEMBL15516990 | 0.76 | TSHR (0.44) | — | |
| SCHEMBL18085576 | 0.76 | TSHR (0.44) | — | |
| SCHEMBL15516988 | 0.76 | TSHR (0.44) | — | |
| SCHEMBL7916590 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2332943-B1 | NOVEL FUSED AMINODIHYDROTHIAZINE DERIVATIVE | EISAI R&D MAN CO LTD (JP) | 2015-04-22 | — | — | EP | disclosed |
| US-8198269-B2 | Fused aminodihydrothiazine derivative | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-06-12 | — | — | US | disclosed |
| US-20100093999-A1 | NOVEL FUSED AMINODIHYDROTHIAZINE DERIVATIVE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-04-15 | — | — | US | disclosed |