Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | NT5E | P21589 | 2/20 | 0.32 |
| ▸ | HINT1 | P49773 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30140997 | 0.87 | TYMP (0.51) | TYMPHPGDTAAR1HINT1TAS1R3 | |
| SCHEMBL24513002 | 0.85 | TYMP (0.45) | TYMPHPGDTAAR1ADORA3TAS1R3 | |
| SCHEMBL19362152 | 0.85 | TYMP (0.45) | TYMPHPGDTAAR1ADORA3TAS1R3 | |
| SCHEMBL1096942 | 0.85 | TYMP (0.45) | TYMPHPGDTAAR1ADORA3TAS1R3 | |
| SCHEMBL19357014 | 0.85 | TYMP (0.36) | TYMPHPGD | |
| SCHEMBL22594612 | 0.81 | TYMP (0.45) | TYMPHPGDADORA3NT5E | |
| SCHEMBL31359570 | 0.81 | TYMP (0.45) | TYMPHPGDADORA3NT5E | |
| SCHEMBL22556252 | 0.81 | TYMP (0.45) | TYMPHPGDADORA3NT5E | |
| SCHEMBL22556249 | 0.81 | TYMP (0.45) | TYMPHPGDADORA3NT5E | |
| SCHEMBL30141048 | 0.80 | TYMP (0.44) | TYMPADORA3ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3430021-A1 | ACYL-PROTECTED L-LNA-GUANOSINE MONOMERS | Roche Innovation Center Copenhagen A/S (DK) | 2019-01-23 | — | — | EP | disclosed |
| WO-2017157672-A1 | ACYL-PROTECTED L-LNA-GUANOSINE MONOMERS | ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) | 2017-09-21 | — | — | WO | disclosed |