Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19356962 | 0.89 | TYMP (0.36) | TYMPHPGD | |
| SCHEMBL22408779 | 0.88 | TYMP (0.36) | TYMPHPGD | |
| SCHEMBL22408780 | 0.88 | TYMP (0.36) | TYMPHPGD | |
| SCHEMBL19356965 | 0.85 | TYMP (0.44) | TYMPHPGD | |
| SCHEMBL22408784 | 0.78 | TYMP (0.37) | TYMPHPGD | |
| SCHEMBL22408783 | 0.78 | TYMP (0.37) | TYMPHPGD | |
| SCHEMBL19362144 | 0.78 | TYMP (0.37) | TYMPHPGD | |
| SCHEMBL26840474 | 0.76 | KDM4E (0.38) | — | |
| SCHEMBL19362146 | 0.76 | KDM4E (0.40) | — | |
| SCHEMBL30140997 | 0.73 | TYMP (0.51) | TYMPHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3430021-A1 | ACYL-PROTECTED L-LNA-GUANOSINE MONOMERS | Roche Innovation Center Copenhagen A/S (DK) | 2019-01-23 | — | — | EP | disclosed |
| WO-2017157672-A1 | ACYL-PROTECTED L-LNA-GUANOSINE MONOMERS | ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) | 2017-09-21 | — | — | WO | disclosed |