SCHEMBL19357751

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29710091	1.00	BTK (0.44)	BTKHSP90AA1KDM4EADRA1DTEAD1
	SCHEMBL19357628	0.87	BTK (0.43)	BTKADRA1DTEAD1TEAD4TEAD2
	SCHEMBL19357663	0.87	BTK (0.46)	BTKTEAD1TEAD4TEAD2TEAD3
	SCHEMBL19357627	0.87	BTK (0.46)	BTKTEAD1TEAD4TEAD2TEAD3
	SCHEMBL29710321	0.87	BTK (0.43)	BTKADRA1DTEAD1TEAD4TEAD2
	SCHEMBL19357939	0.86	BTK (0.44)	BTKKDM4ETEAD1TEAD4TEAD2
	SCHEMBL29710124	0.84	TEAD1 (0.39)	BTKHSP90AA1KDM4ETEAD1TEAD4
	SCHEMBL19357643	0.84	TEAD1 (0.39)	BTKHSP90AA1KDM4ETEAD1TEAD4
	SCHEMBL19357959	0.81	BTK (0.39)	BTKTEAD1TEAD4TEAD2TEAD3
	SCHEMBL19374771	0.81	BTK (0.45)	BTKTEAD1TEAD4TEAD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.