SCHEMBL1935794

SCHEMBL1935794

CSC(C)c1cccc(N)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 6/20 0.44
CASP1 P29466 2/20 0.44
RECQL P46063 1/20 0.44
CPN1 P15169 1/20 0.40
CPB2 Q96IY4 1/20 0.40
ALDH1A1 P00352 5/20 0.38
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA9 Q16790 2/20 0.37
CA12 O43570 1/20 0.37
CA7 P43166 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CA14 Q9ULX7 1/20 0.37
MAPKAPK2 P49137 1/20 0.36
ADRB1 P08588 1/20 0.36
MIF P14174 1/20 0.36
HTR2A P28223 1/20 0.36
ADRA1A P35348 1/20 0.36
HTR2B P41595 1/20 0.36
MAOA P21397 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21880676 0.82 CYP3A4 (0.42) CYP3A4CASP1RECQLCPN1CPB2
SCHEMBL1935120 0.79 CPN1 (0.40) CYP3A4CASP1RECQLCPN1CPB2
SCHEMBL272384 0.78 CYP3A4 (0.52) CYP3A4CASP1RECQLCPN1CPB2
SCHEMBL30349751 0.78 CYP3A4 (0.52) CYP3A4CASP1RECQLCPN1CPB2
SCHEMBL104340 0.78 CYP3A4 (0.52) CYP3A4CASP1RECQLCPN1CPB2
SCHEMBL2023304 0.76 CYP3A4 (0.50) CYP3A4CASP1RECQLCPN1CPB2
SCHEMBL31226349 0.76 CYP3A4 (0.50) CYP3A4CASP1RECQLCPN1CPB2
SCHEMBL8281139 0.76 CYP3A4 (0.50) CYP3A4CASP1RECQLCPN1CPB2
SCHEMBL3476361 0.76 CYP3A4 (0.50) CYP3A4CASP1RECQLCPN1CPB2
SCHEMBL8281143 0.76 CYP3A4 (0.50) CYP3A4CASP1RECQLCPN1CPB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2331512-A1 ALKOXY-SUBSTITUTED AND ALKYLTHIO-SUBSTITUTED ANILINOPYRIMIDINES Bayer CropScience AG (DE) 2011-06-15 EP disclosed
WO-2010025833-A1 ALKOXY-SUBSTITUTED AND ALKYLTHIO-SUBSTITUTED ANILINOPYRIMIDINES BAYER CROPSCIENCE AG (DE) 2010-03-11 WO disclosed