SCHEMBL19358288

SCHEMBL19358288

O=Cc1ccc(OCCCC(O)=S)cc1O

nearest known ligand 0.63

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.51
TRIM24 O15164 1/20 0.51
TRIM33 Q9UPN9 1/20 0.51
POLB P06746 1/20 0.46
MAPT P10636 1/20 0.46
ALB P02768 1/20 0.38
PPARD Q03181 1/20 0.38
ERN1 O75460 1/20 0.37
TNF P01375 1/20 0.37
NOD1 Q9Y239 1/20 0.37
LMNA P02545 1/20 0.37
STAT3 P40763 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HKDC1 Q2TB90 1/20 0.37
NOD2 Q9HC29 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19358277 0.87 TRIM24 (0.53) TYRTRIM24TRIM33POLBMAPT
SCHEMBL19358286 0.82 TYR (0.51) TYRTRIM24TRIM33POLBMAPT
SCHEMBL2558549 0.82 ALB (0.57) TYRTRIM24TRIM33POLBMAPT
SCHEMBL3195593 0.81 TYR (0.57) TYRTRIM24TRIM33POLBMAPT
SCHEMBL4556765 0.81 TYR (0.62) TYRTRIM24TRIM33POLBMAPT
SCHEMBL10584941 0.80 TYR (0.59) TYRTRIM24TRIM33POLBMAPT
SCHEMBL20339391 0.79 TYR (0.63) TYRTRIM24TRIM33POLBMAPT
SCHEMBL16873694 0.79 TYR (0.54) TYRTRIM24TRIM33POLBMAPT
SCHEMBL22146620 0.79 TYR (0.63) TYRTRIM24TRIM33POLBMAPT
SCHEMBL7323609 0.79 TRIM24 (0.58) TYRTRIM24TRIM33POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11149058-B2 Multi-functional chemical agents, and the method for protein modification DEPARTMENT OF BIOTECHNOLOGY (IN) 2021-10-19 US disclosed
US-20210163526-A9 Multi-Functional Chemical Agents, and the Method for Protein Modification DEPARTMENT OF BIOTECHNOLOGY (IN) 2021-06-03 US disclosed
US-20190085020-A1 Multi-Functional Chemical Agents, and the Method for Protein Modification DEPARTMENT OF BIOTECHNOLOGY (IN) 2019-03-21 US disclosed
EP-3442987-A1 MULTI-FUNCTIONAL CHEMICAL AGENTS, AND THE METHOD FOR PROTEIN MODIFICATION Department of Biotechnology (IN) 2019-02-20 EP disclosed
WO-2017158612-A1 MULTI-FUNCTIONAL CHEMICAL AGENTS, AND THE METHOD FOR PROTEIN MODIFICATION DEPARTMENT OF BIOTECHNOLOGY (IN) 2017-09-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11149058-B2 Multi-functional chemical agents, and the method for protein modification FN1, LCP1, NPM1 TYR 4318/4885TRIM24 447/4885TRIM33 2240/4885
US-20190085020-A1 Multi-Functional Chemical Agents, and the Method for Protein Modification FN1, LCP1, NPM1 TYR 4318/4885TRIM24 447/4885TRIM33 2240/4885
US-20210163526-A9 Multi-Functional Chemical Agents, and the Method for Protein Modification FN1, LCP1, NPM1 TYR 4318/4885TRIM24 447/4885TRIM33 2240/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.