Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.64 |
| ▸ | PELI1 | Q96FA3 | 2/20 | 0.59 |
| ▸ | NAAA | Q02083 | 1/20 | 0.58 |
| ▸ | EGFR | P00533 | 1/20 | 0.58 |
| ▸ | SNCA | P37840 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19369311 | 1.00 | APP (0.64) | APPPELI1NAAAEGFRSNCA | |
| SCHEMBL8756992 | 0.91 | APP (0.62) | APPPELI1NAAAEGFRHTR1A | |
| SCHEMBL8756987 | 0.91 | APP (0.62) | APPPELI1NAAAEGFRHTR1A | |
| SCHEMBL8756981 | 0.91 | APP (0.62) | APPPELI1NAAAEGFRHTR1A | |
| SCHEMBL6659147 | 0.86 | EGFR (0.56) | APPPELI1NAAAEGFRMAPT | |
| SCHEMBL6659156 | 0.86 | EGFR (0.56) | APPPELI1NAAAEGFRMAPT | |
| SCHEMBL19369308 | 0.85 | APP (0.65) | APPPELI1EGFRMAPTHTR1A | |
| SCHEMBL19358956 | 0.85 | APP (0.65) | APPPELI1EGFRMAPTHTR1A | |
| SCHEMBL8756763 | 0.84 | EGFR (0.68) | APPPELI1NAAAEGFRMAPT | |
| SCHEMBL8756769 | 0.84 | EGFR (0.68) | APPPELI1NAAAEGFRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017161093-A1 | CAFFEIC ACID DERIVATIVES AND USES THEREOF | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2017-09-21 | — | — | WO | claimed |
| WO-2017161093-A1 | CAFFEIC ACID DERIVATIVES AND USES THEREOF | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2017-09-21 | — | — | WO | disclosed |