Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.62 |
| ▸ | EGFR | P00533 | 1/20 | 0.59 |
| ▸ | PELI1 | Q96FA3 | 2/20 | 0.57 |
| ▸ | NAAA | Q02083 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | HTR2C | P28335 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8756987 | 1.00 | APP (0.62) | APPEGFRPELI1NAAAHTR1A | |
| SCHEMBL8756981 | 1.00 | APP (0.62) | APPEGFRPELI1NAAAHTR1A | |
| SCHEMBL19369311 | 0.91 | APP (0.64) | APPEGFRPELI1NAAAHTR1A | |
| SCHEMBL19358993 | 0.91 | APP (0.64) | APPEGFRPELI1NAAAHTR1A | |
| SCHEMBL6659156 | 0.90 | EGFR (0.56) | APPEGFRPELI1NAAAHTR1A | |
| SCHEMBL6659147 | 0.90 | EGFR (0.56) | APPEGFRPELI1NAAAHTR1A | |
| SCHEMBL23344644 | 0.88 | APP (0.55) | APPEGFRPELI1HTR1AHTR2C | |
| SCHEMBL6653659 | 0.86 | APP (0.62) | APPEGFRPELI1HTR1AHTR2C | |
| SCHEMBL6653655 | 0.86 | APP (0.62) | APPEGFRPELI1HTR1AHTR2C | |
| SCHEMBL19369308 | 0.86 | APP (0.65) | APPEGFRPELI1HTR1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574879-B1 | Reversible heat-sensitive recording material | MITSUBISHI PAPER MILLS LTD (JP) | 1997-05-02 | — | — | EP | disclosed |
| US-5395815-A | Phenolic compound electron acceptor; images; contrast; stability | MITSUBISHI PAPER MILLS LIMITED (JP) | 1995-03-07 | — | — | US | disclosed |
| EP-0574879-A1 | Reversible heat-sensitive recording material | MITSUBISHI PAPER MILLS, LTD. (JP) | 1993-12-22 | — | — | EP | disclosed |