Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 11/20 | 0.46 |
| ▸ | BRAF | P15056 | 2/20 | 0.46 |
| ▸ | GSK3A | P49840 | 13/20 | 0.45 |
| ▸ | SRC | P12931 | 7/20 | 0.45 |
| ▸ | SYK | P43405 | 7/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | LYN | P07948 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1936512 | 0.95 | MAPK14 (0.47) | MAPK14BRAFGSK3ASRCSYK | |
| SCHEMBL1936877 | 0.89 | MAPK14 (0.49) | MAPK14BRAFGSK3ASRCSYK | |
| SCHEMBL2671405 | 0.88 | MAPK14 (0.47) | MAPK14BRAFGSK3ASRCSYK | |
| SCHEMBL1936510 | 0.88 | MAPK14 (0.47) | MAPK14BRAFGSK3ASRCSYK | |
| SCHEMBL1935811 | 0.87 | MAPK14 (0.47) | MAPK14BRAFGSK3ASRCSYK | |
| SCHEMBL1936181 | 0.86 | BRAF (0.53) | MAPK14BRAF | |
| SCHEMBL1936256 | 0.86 | MAPK14 (0.46) | MAPK14BRAFGSK3ASRCSYK | |
| SCHEMBL1935992 | 0.86 | GSK3A (0.47) | MAPK14BRAFGSK3ASRCSYK | |
| SCHEMBL1935948 | 0.84 | MAPK14 (0.47) | MAPK14BRAFGSK3ASRCSYK | |
| SCHEMBL1936534 | 0.82 | MAPK14 (0.51) | MAPK14BRAFGSK3ASRCSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331506-B1 | NOVEL BENZAMIDES, PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM INT (DE) | 2013-07-03 | — | — | EP | disclosed |
| EP-2331506-A1 | NOVEL BENZAMIDES, PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010026095-A1 | NOVEL BENZAMIDES, PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-03-11 | — | — | WO | disclosed |