Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1935948 | 0.92 | MAPK14 (0.47) | BRAFMAPK14 | |
| SCHEMBL1934475 | 0.89 | BRAF (0.56) | BRAFMAPK14 | |
| SCHEMBL2671063 | 0.88 | BRAF (0.54) | BRAFMAPK14 | |
| SCHEMBL1935773 | 0.88 | BRAF (0.54) | BRAFMAPK14 | |
| SCHEMBL1936737 | 0.87 | BRAF (0.52) | BRAFMAPK14 | |
| SCHEMBL1935930 | 0.87 | BRAF (0.54) | BRAFMAPK14 | |
| SCHEMBL1936661 | 0.87 | BRAF (0.57) | BRAF | |
| SCHEMBL1935910 | 0.86 | MAPK14 (0.46) | BRAFMAPK14 | |
| SCHEMBL1934582 | 0.85 | BRAF (0.54) | BRAF | |
| SCHEMBL15062880 | 0.84 | BRAF (0.64) | BRAFMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331506-B1 | NOVEL BENZAMIDES, PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM INT (DE) | 2013-07-03 | — | — | EP | disclosed |
| EP-2331506-A1 | NOVEL BENZAMIDES, PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010026095-A1 | NOVEL BENZAMIDES, PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-03-11 | — | — | WO | disclosed |