Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19359787 | 0.84 | MAPT (0.42) | MAPTALDH1A1FFAR1 | |
| SCHEMBL25392616 | 0.83 | MAPT (0.50) | MAPTALDH1A1FFAR1 | |
| SCHEMBL1127763 | 0.83 | MAPT (0.50) | MAPTALDH1A1FFAR1 | |
| SCHEMBL4438761 | 0.82 | MAPT (0.43) | MAPTALDH1A1FFAR1 | |
| SCHEMBL18923856 | 0.82 | MAPT (0.43) | MAPTCTSKALDH1A1FFAR1 | |
| SCHEMBL2988909 | 0.82 | MAPT (0.43) | MAPTALDH1A1FFAR1 | |
| SCHEMBL2991296 | 0.82 | MAPT (0.43) | MAPTALDH1A1FFAR1 | |
| SCHEMBL6898236 | 0.81 | TSHR (0.43) | CTSKALDH1A1 | |
| SCHEMBL4736454 | 0.80 | MAPT (0.42) | MAPTALDH1A1FFAR1 | |
| SCHEMBL10662849 | 0.80 | MAPT (0.42) | MAPTALDH1A1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10011569-B2 | Process for synthesizing oxidized lactam compounds | ALKERMES PHARMA IRELAND LIMITED (IE) | 2018-07-03 | — | — | US | disclosed |
| US-20170267639-A1 | Process for Synthesizing Oxidized Lactam Compounds | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2017-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170267639-A1 | Process for Synthesizing Oxidized Lactam Compounds | COASY, DHPS, OXA1L | MAPT 3460/4885CTSK 2222/4885ALDH1A1 113/4885 |
| US-10011569-B2 | Process for synthesizing oxidized lactam compounds | COASY, DHPS, OXA1L | MAPT 3460/4885CTSK 2222/4885ALDH1A1 113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.