SCHEMBL19359883

SCHEMBL19359883

CC1(C)c2ccccc2-c2ccc(-n3c4ccccc4c4c5c6ccccc6n(-c6cccc(-n7c8ccccc8c8ccccc87)c6)c5ccc43)cc21

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PGR P06401 6/20 0.34
DUSP3 P51452 1/20 0.31
PDE4A P27815 1/20 0.30
PDE4B Q07343 1/20 0.30
PDE4C Q08493 1/20 0.30
PDE4D Q08499 1/20 0.30
PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18121218 0.95 KDM4E (0.35) KDM4EATML3MBTL1PGRPDK2
SCHEMBL18121208 0.94 KDM4E (0.42) KDM4EATML3MBTL1PGRPDK2
SCHEMBL18126103 0.94 KDM4E (0.36) KDM4EATML3MBTL1PGRPDK2
SCHEMBL19359886 0.93 KDM4E (0.43) KDM4EATML3MBTL1PGR
SCHEMBL18416321 0.92 MEN1 (0.39) KDM4EATML3MBTL1PGRPDK2
SCHEMBL18121222 0.91 KDM4E (0.33) KDM4EATML3MBTL1PGRPDK2
SCHEMBL20926864 0.91 KDM4E (0.33) KDM4EATML3MBTL1PGRPDK2
SCHEMBL18121205 0.91 ATM (0.35) KDM4EATML3MBTL1PGRPDK2
SCHEMBL18086278 0.90 PGR (0.34) KDM4EATML3MBTL1PGRPDK2
SCHEMBL18121214 0.90 KDM4E (0.32) KDM4EATML3MBTL1PGRPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210351362-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-11-11 US disclosed
US-11094891-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-08-17 US disclosed
US-20170271598-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-09-21 US disclosed
US-20170271598-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-09-21 US disclosed