Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9322043 | 0.78 | CYP3A4 (0.33) | ATMCYP3A4 | |
| SCHEMBL7296925 | 0.72 | DNM1 (0.34) | TSHR | |
| SCHEMBL3139537 | 0.72 | CA1 (0.33) | TSHR | |
| SCHEMBL7452131 | 0.71 | CA1 (0.35) | TSHR | |
| SCHEMBL6131279 | 0.71 | CA1 (0.35) | TSHR | |
| SCHEMBL10483577 | 0.71 | CA1 (0.35) | TSHR | |
| SCHEMBL7668434 | 0.70 | CYP3A4 (0.37) | TSHRATMCYP3A4 | |
| SCHEMBL8422500 | 0.66 | ATM (0.38) | TSHRATMCYP3A4 | |
| SCHEMBL10773593 | 0.65 | TSHR (0.40) | TSHR | |
| SCHEMBL4987261 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011527701-A | — | — | 2011-11-04 | — | — | JP | claimed |
| EP-2331503-A1 | 4-PHENOXYMETHYLPIPERIDINES AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2011-06-15 | — | — | EP | claimed |
| WO-2010006191-A1 | 4-PHENOXYMETHYLPIPERIDINES AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2010-01-14 | — | — | WO | claimed |