Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 13/20 | 0.74 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19360638 | 0.82 | RORC (0.63) | RORC | |
| SCHEMBL19360452 | 0.82 | RORC (0.63) | RORCNR1H4EPHX2 | |
| SCHEMBL19360310 | 0.78 | RORC (0.77) | RORCEPHX2 | |
| SCHEMBL19360653 | 0.78 | RORC (0.62) | RORC | |
| SCHEMBL19360514 | 0.78 | RORC (0.62) | RORC | |
| SCHEMBL19360348 | 0.77 | RORC (0.86) | RORC | |
| SCHEMBL19360386 | 0.77 | RORC (0.86) | RORC | |
| SCHEMBL19360330 | 0.77 | RORC (0.64) | RORC | |
| SCHEMBL19360334 | 0.77 | RORC (0.85) | RORC | |
| SCHEMBL19360445 | 0.77 | RORC (0.85) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017157332-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATIONS THEREOF | 江苏恒瑞医药股份有限公司 | 2017-09-21 | — | — | WO | disclosed |