Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 16/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19360310 | 0.88 | RORC (0.77) | RORCEPHX2PPARG | |
| SCHEMBL19360376 | 0.86 | RORC (0.79) | RORC | |
| SCHEMBL19360538 | 0.86 | RORC (0.65) | RORCEPHX2PPARG | |
| SCHEMBL19360509 | 0.85 | RORC (0.64) | RORCEPHX2PPARG | |
| SCHEMBL19360411 | 0.80 | RORC (0.61) | RORC | |
| SCHEMBL19360643 | 0.78 | RORC (0.61) | RORCEPHX2PPARG | |
| SCHEMBL19360380 | 0.78 | RORC (0.78) | RORC | |
| SCHEMBL19360309 | 0.77 | RORC (1.00) | RORC | |
| SCHEMBL22512495 | 0.76 | RORC (0.53) | RORC | |
| SCHEMBL19360354 | 0.76 | RORC (0.59) | RORCEPHX2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017157332-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATIONS THEREOF | 江苏恒瑞医药股份有限公司 | 2017-09-21 | — | — | WO | disclosed |