Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ASPH | Q12797 | 1/20 | 0.33 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1936043 | 1.00 | P4HTM (0.37) | P4HTMKDM4EHCAR2NAPRTP4HA1 | |
| SCHEMBL2644292 | 0.82 | MAPK1 (0.42) | KDM4EALDH1A1HSD17B10L3MBTL1MAPK1 | |
| SCHEMBL2644296 | 0.82 | MAPK1 (0.42) | KDM4EALDH1A1HSD17B10L3MBTL1MAPK1 | |
| SCHEMBL990534 | 0.79 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL990536 | 0.79 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL6822704 | 0.72 | ALDH1A1 (0.46) | P4HTMKDM4EHCAR2NAPRTALDH1A1 | |
| SCHEMBL6822705 | 0.72 | ALDH1A1 (0.46) | P4HTMKDM4EHCAR2NAPRTALDH1A1 | |
| SCHEMBL19556490 | 0.72 | P4HTM (0.37) | P4HTMKDM4EHCAR2NAPRTP4HA1 | |
| SCHEMBL19556491 | 0.72 | P4HTM (0.37) | P4HTMKDM4EHCAR2NAPRTP4HA1 | |
| SCHEMBL30112013 | 0.72 | P4HTM (0.37) | P4HTMKDM4EHCAR2NAPRTP4HA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2332943-A1 | NOVEL FUSED AMINODIHYDROTHIAZINE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2011-06-15 | — | — | EP | disclosed |