Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 17/20 | 0.42 |
| ▸ | RORA | P35398 | 1/20 | 0.40 |
| ▸ | RORB | Q92753 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19360493 | 0.92 | RORC (0.47) | RORCNAMPT | |
| SCHEMBL19360340 | 0.87 | RORC (0.52) | RORCNAMPT | |
| SCHEMBL19360342 | 0.80 | RORC (0.53) | RORC | |
| SCHEMBL19360484 | 0.80 | RORC (0.51) | RORCNAMPT | |
| SCHEMBL19360627 | 0.75 | RORC (0.61) | RORC | |
| SCHEMBL19360631 | 0.75 | RORC (0.50) | RORCNAMPT | |
| SCHEMBL19360628 | 0.75 | RORC (0.50) | RORCNAMPT | |
| SCHEMBL28589124 | 0.74 | RORC (0.50) | RORC | |
| SCHEMBL19360501 | 0.74 | RORC (0.50) | RORC | |
| SCHEMBL19360507 | 0.74 | RORC (0.50) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017157332-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATIONS THEREOF | 江苏恒瑞医药股份有限公司 | 2017-09-21 | — | — | WO | disclosed |