Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25039128 | 1.00 | CA12 (0.42) | CA12CA1CA2CA9SLC7A5 | |
| SCHEMBL19387347 | 0.88 | SLC7A5 (0.38) | CA12CA1CA2CA9SLC7A5 | |
| SCHEMBL19387340 | 0.88 | SLC7A5 (0.38) | CA12CA1CA2CA9SLC7A5 | |
| SCHEMBL19750463 | 0.88 | SLC7A5 (0.38) | CA12CA1CA2CA9SLC7A5 | |
| SCHEMBL15623815 | 0.86 | SLC7A5 (0.48) | SLC7A5CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL26359428 | 0.86 | SLC7A5 (0.48) | SLC7A5CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL13224082 | 0.86 | RARB (0.37) | SLC7A5CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL18672811 | 0.86 | RARB (0.37) | SLC7A5CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL24159912 | 0.85 | CYP19A1 (0.41) | CA12CA1CA2CA9CYP19A1 | |
| SCHEMBL20919191 | 0.84 | RARB (0.36) | SLC7A5DPP4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170266172-A1 | Compositions and Uses of Amidine Derivatives | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2017-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170266172-A1 | Compositions and Uses of Amidine Derivatives | HRH3, HRH2, HRH1 | CA12 2555/4885CA1 2772/4885CA2 1688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.