Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.41 |
| ▸ | LAP3 | P28838 | 5/20 | 0.40 |
| ▸ | ANPEP | P15144 | 5/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20747649 | 0.83 | SLC7A5 (0.41) | SLC7A5LAP3TSHRDPP4CHRM2 | |
| SCHEMBL2300123 | 0.83 | SLC7A5 (0.41) | SLC7A5LAP3TSHRDPP4CHRM2 | |
| SCHEMBL22891028 | 0.83 | SLC7A5 (0.41) | SLC7A5LAP3TSHRDPP4CHRM2 | |
| SCHEMBL27824244 | 0.83 | SLC7A5 (0.41) | SLC7A5LAP3TSHRDPP4CHRM2 | |
| SCHEMBL2297294 | 0.83 | SLC7A5 (0.41) | SLC7A5LAP3TSHRDPP4CHRM2 | |
| SCHEMBL17539381 | 0.83 | SLC7A5 (0.41) | SLC7A5LAP3TSHRDPP4CHRM2 | |
| SCHEMBL27803439 | 0.83 | SLC7A5 (0.41) | SLC7A5LAP3TSHRDPP4CHRM2 | |
| SCHEMBL23656867 | 0.82 | SLC7A5 (0.44) | SLC7A5LAP3ANPEPERAP1SLC1A3 | |
| SCHEMBL17662348 | 0.82 | SLC7A5 (0.44) | SLC7A5LAP3ANPEPERAP1SLC1A3 | |
| SCHEMBL21985751 | 0.82 | DPP4 (0.40) | SLC7A5LAP3ANPEPERAP1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10905683-B2 | Compositions and uses of amidine derivatives | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-02-02 | — | — | US | disclosed |
| US-20170266172-A1 | Compositions and Uses of Amidine Derivatives | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2017-09-21 | — | — | US | disclosed |
| US-20170266172-A1 | Compositions and Uses of Amidine Derivatives | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2017-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10905683-B2 | Compositions and uses of amidine derivatives | HRH3, HRH2, HRH1 | SLC7A5 1328/4885LAP3 1599/4885ANPEP 587/4885 |
| US-20170266172-A1 | Compositions and Uses of Amidine Derivatives | HRH3, HRH2, HRH1 | SLC7A5 1328/4885LAP3 1599/4885ANPEP 587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.