Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 4/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.32 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | LAP3 | P28838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2297294 | 1.00 | SLC7A5 (0.41) | SLC7A5MAPTFAAHDPP4TSHR | |
| SCHEMBL27824244 | 1.00 | SLC7A5 (0.41) | SLC7A5MAPTFAAHDPP4TSHR | |
| SCHEMBL22891028 | 1.00 | SLC7A5 (0.41) | SLC7A5MAPTFAAHDPP4TSHR | |
| SCHEMBL20747649 | 1.00 | SLC7A5 (0.41) | SLC7A5MAPTFAAHDPP4TSHR | |
| SCHEMBL17539381 | 1.00 | SLC7A5 (0.41) | SLC7A5MAPTFAAHDPP4TSHR | |
| SCHEMBL2300123 | 1.00 | SLC7A5 (0.41) | SLC7A5MAPTFAAHDPP4TSHR | |
| SCHEMBL22890984 | 0.85 | DPP4 (0.42) | MAPTDPP4DPP8DPP9DPP7 | |
| SCHEMBL8751922 | 0.85 | DPP4 (0.42) | MAPTDPP4DPP8DPP9DPP7 | |
| SCHEMBL8861409 | 0.83 | SLC7A5 (0.43) | SLC7A5MAPTLAP3 | |
| SCHEMBL19474050 | 0.83 | FAAH (0.41) | SLC7A5FAAHDPP4TSHRCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101983061-A | Certain chemical entities, compositions and methods | CYTOKINETICS INC | 2011-03-02 | — | — | CN | disclosed |