Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.32 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14910075 | 1.00 | KDM4E (0.53) | KDM4EL3MBTL1ATMTDP1CYP3A4 | |
| SCHEMBL30775140 | 1.00 | KDM4E (0.53) | KDM4EL3MBTL1ATMTDP1CYP3A4 | |
| SCHEMBL14910575 | 1.00 | KDM4E (0.53) | KDM4EL3MBTL1ATMTDP1CYP3A4 | |
| SCHEMBL14909983 | 1.00 | KDM4E (0.53) | KDM4EL3MBTL1ATMTDP1CYP3A4 | |
| SCHEMBL14948506 | 0.93 | KDM4E (0.52) | KDM4EL3MBTL1ATMTDP1CYP3A4 | |
| SCHEMBL801509 | 0.93 | L3MBTL1 (0.62) | KDM4EL3MBTL1ATMTDP1CYP3A4 | |
| SCHEMBL781505 | 0.93 | L3MBTL1 (0.62) | KDM4EL3MBTL1ATMTDP1CYP3A4 | |
| SCHEMBL801793 | 0.90 | KDM4E (0.57) | KDM4EL3MBTL1ATMTDP1CYP3A4 | |
| SCHEMBL28006122 | 0.90 | L3MBTL1 (0.61) | KDM4EL3MBTL1ATMTDP1CYP3A4 | |
| SCHEMBL782778 | 0.88 | KDM4E (0.52) | KDM4EL3MBTL1ATMTDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2589643-B1 | HIGHLY EFFICIENT CARBAZOLE-BASED COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME | SK CHEMICALS CO LTD (KR) | 2017-09-20 | — | — | EP | disclosed |