Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.34 |
| ▸ | CNR1 | P21554 | 4/20 | 0.34 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.32 |
| ▸ | CSNK1E | P49674 | 3/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1936635 | 0.97 | TYK2 (0.33) | CNR2CNR1EGFRBTKTYK2 | |
| SCHEMBL2465747 | 0.85 | CNR2 (0.34) | CNR2CNR1ABHD6FAAHEGFR | |
| SCHEMBL2432013 | 0.85 | CSF1R (0.31) | CNR2ABHD6TYK2 | |
| SCHEMBL1934770 | 0.85 | CSNK1D (0.37) | BTKCSNK1DCSNK1E | |
| SCHEMBL1936633 | 0.83 | CSNK1D (0.33) | EGFRBTKCSNK1DCSNK1EKCNH2 | |
| SCHEMBL2431185 | 0.81 | RET (0.37) | BTKCSNK1DCSNK1EKCNH2 | |
| SCHEMBL2464594 | 0.80 | CYP2C8 (0.38) | EGFRBTKCSNK1DCSNK1EKCNH2 | |
| SCHEMBL2467318 | 0.80 | BTK (0.34) | BTKCSNK1DCSNK1EKCNH2 | |
| SCHEMBL2997319 | 0.79 | CYP2C8 (0.42) | EGFRBTKCSNK1DCSNK1EKCNH2 | |
| SCHEMBL2469426 | 0.78 | CYP2C8 (0.48) | EGFRBTKCSNK1DCSNK1EKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331502-A2 | COMPOUNDS FOR THE TREATMENT OF HEPATITIS C | Bristol-Myers Squibb Company (US) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010030538-A2 | COMPOUNDS FOR THE TREATMENT OF HEPATITIS C | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-03-18 | — | — | WO | disclosed |