Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1936635 | 0.88 | TYK2 (0.33) | TYK2CNR2 | |
| SCHEMBL1936236 | 0.85 | CNR2 (0.34) | TYK2CNR2ABHD6 | |
| SCHEMBL2465554 | 0.82 | CYP2C8 (0.42) | — | |
| SCHEMBL1934770 | 0.81 | CSNK1D (0.37) | — | |
| SCHEMBL1936633 | 0.79 | CSNK1D (0.33) | — | |
| SCHEMBL2431185 | 0.78 | RET (0.37) | — | |
| SCHEMBL2465747 | 0.78 | CNR2 (0.34) | CNR2ABHD6 | |
| SCHEMBL2469426 | 0.78 | CYP2C8 (0.48) | — | |
| SCHEMBL2464594 | 0.77 | CYP2C8 (0.38) | — | |
| SCHEMBL2467318 | 0.77 | BTK (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2545050-A1 | COMPOUNDS FOR THE TREATMENT OF HEPATITIS C | Bristol-Myers Squibb Company (US) | 2013-01-16 | — | — | EP | claimed |
| WO-2011112186-A1 | COMPOUNDS FOR THE TREATMENT OF HEPATITIS C | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-09-15 | — | — | WO | claimed |